The Aesthetics Advisor

The prospect of slowing, stopping, or even reversing the aging process has captivated humankind for millennia. The competitors of the Rejuvenation Olympics (RO) hope the elusive fountain of youth may finally be within reach. “Where you win by never crossing the finish line,” teases the website. A special leaderboard charts progress based on the age of participants’ cells and tissues—beyond just years accrued. Bryan Johnson , a 46-year-old multimillionaire entrepreneur and biohacker, conceived RO as the ultimate anti-aging proving ground. While Mr. Johnson ranks seventh in the top 20—despite pumping $2 million a year into longevity protocols—an unlikely figure is ahead of him: 61-year-old Dave Pascoe, boasting a mid-30s biological age. How does he do it? From Stress to Success: Daily Rituals for Rejuvenation More than two decades ago, Mr. Pascoe cared for his cancer-stricken parents—a very stressful period in his life, he told The Epoch Times. Exercise became his coping mechanism. B...

Magnesium, an essential mineral involved in more than 300 metabolic reactions, 1   may also play an important role in liver health. Due to the way it interacts with your gut microbiome, magnesium may offer protection from liver damage caused by one of the most common liver toxins — acetaminophen, also known as Tylenol. 2 Acetaminophen overdose is one of the leading causes of liver injury in the U.S. and some parts of Europe. In these areas, acetaminophen is responsible for more than 50% of acute liver failure cases. 3 Treatment for acetaminophen-induced liver failure is limited, with liver transplant the only option in severe cases, making liver injury caused by acetaminophen an emerging “public health issue.” 4  Magnesium, however, has the potential to help, according to research published in Cell Host & Microbe. Magnesium Alleviates Acetaminophen-Induced Liver Failure When excess amounts of acetaminophen are metabolized, it depletes glutathione and increases N-acetyl-p-b...

L-glutamine for eczema? L-glutamine for a leaky gut ? Yes, l-glutamine shows much promise for healing eczema and a leaky gut. Glutamine is considered “conditionally essential” because it can be synthesized from glutamate when total protein is adequate, yet it can become depleted to dangerous levels that require supplementation during illness, injury, and surgery.   L-Glutamine for Eczema The Google search term 'l-glutamine for leaky gut', returns over 150,000 results. Similarly, the Google search term 'l-glutamine for autoimmune', shows nearly 1 million results. And, of course, 'l-glutamine for eczema', returns over 300,000 results. So, clearly, a lot is being written about l-glutamine for eczema, l-glutamine for a leaky gut, and l-glutamine for other gastrointestinal problems. L-glutamine is sometimes just called glutamine. But, what is this l-glutamine? L-glutamine is...

Numerous studies show that dietary energy restriction is a general metabolic therapy that naturally lowers circulating glucose levels and significantly reduces the growth and progression of numerous tumor types, including cancers of the breast, brain, colon, pancreas, lung, and prostate. (245-251) An impressive body of evidence indicates that dietary energy restriction can retard the growth rate of many tumors regardless of the specific genetic defects expressed within the tumor. (245-251) Hyperglycemia with high insulin levels is associated with tumor recurrence. (58, 252) Sugar sweetened beverages are associated with an increased risk of cancer. (253-255) Both experimental and clinical data suggest that fructose, particularly fructose-corn syrup, to be more carcinogenic than glucose. (229, 256, 257) As demonstrated by Dr. Otto Warburg, almost all cancer cells are dependent on glucose as a metabolic fuel via aerobic glycolysis, (21, 22) with hyperglycemia being a potent promotor o...

One of the most promising approaches in cellular therapies is immunotherapies using engineered T cells or natural killer (NK) cells expressing chimeric antigen receptors (CARs). Will CAR-NK cell therapies overshadow traditional CAR-T options for the treatment of some cancers?   Recently researchers have tried to modify natural killer (NK) cells with chimeric antigen receptors (CAR) to increase potential to bind and destroy cancer cells, known as NK cell therapy. Here we describe the differences between CAR T cell therapies and CAR NK cell therapies to consider when developing cancer treatments for patients. What is CAR-T? T cells are part of the adaptive immune system and are intended to generate a long lasting protective immune response. By engineering T cells with the Natural Killer Group 2D (NKG2D) receptor, they become NKG2D CAR T cell therapies. What is CAR-NK?  NK cells are a part of the innate immune system and are the first line of defense against foreign infections a...