This May Lead to 40-Fold Increased Risk of Schizophrenia: Study
The deletion of a single gene and the crippling effects this has on mitochondria may be responsible for a 40-fold increased risk of developing a devastating mental illness, a new study finds. For decades, researchers have theorized that several genetic underpinnings play a critical role in the development of schizophrenia. But an investigation led by scientists at Emory University and Rutgers published in Science Advances reveals that a missing gene 3q29 could cause the psychiatric disorder due to the significant adverse impact its absence has on mitochondrial function. The 3q29 gene is a micro portion of chromosome 3. The consequences of a lack of this small piece of DNA in each cell vary widely, with some individuals ending up with no problems at all. In contrast, others may suffer from more severe things like delayed development, intellectual disabilities, and behavioral and mental health issues. About ...