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8 Best Vitamin D3 and K2 Supplements 2025: Benefits, Reviews and Prices

By Dr Frank Yap, MD
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Most people in the United States consume less than recommended amounts of vitamin D . An analysis of data from the 2017–2018 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 4.3 mcg in men, 3.8 mcg in women, and 5 mcg (200 IU) in children aged 2–19 years ( NHANES 2017 - 2018 ). What Is Vitamin D? Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune system needs vitamin D to fight off invading bacteria and viruses. Together with calcium, vitamin D also helps protect older adults from osteoporosis. Vitamin D is found in cells throughout the body. Vitamin D Market Size The Global Vitamin D Market size was ...
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Fenbendazole Joe Tippens Protocol: A Step-by-Step Guide

By Dr Frank Yap, MD
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If you have been diagnosed with cancer, or have a loved one that is suffering from cancer, chances are you have heard about the Joe Tippens Cancer Protocol. The Fenbendazole Cancer Protocol has been gaining rapid interest over the past years following some fenbendazole advanced cancer success stories. Joe Tippens founded the protocol after he was told a story about a scientist at Merck Animal Health that had been performing cancer research on mice. The research included injecting different types of cancers into different mice body parts. The scientists discovered, through trial and error, a product in their canine product line, fenbendazole, that was batting 1.000 in killing these different cancers in the mice. The scientist was later diagnosed with stage 4 brain cancer and was given a grim prognosis of only three months to live. She decided to try the fenbendazole, and after six weeks, showed a clean scan. Joe Tippens had been initially diagnosed with small...
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7 Best Cetylpyridinium Chloride Mouthwash Brands 2025

By Dr Frank Yap, MD
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A meta-analysis of 3 studies (C19early 2025) concluded that CPC (CetylPyridinium Chloride) may significantly lower risk with  viral clearance . One study shows significant benefit. Meta analysis using the most serious outcome reported shows 83% [6‑97%] lower risk . Results are consistent with early treatment being more effective than late treatment. A study, published in Nature ( Takeda 2022 ) concluded that CPC (CetylPyridinium Chloride) may inhibit SARS-CoV-2 infection even at lower concentrations. Another team of international scientists has also demonstrated the usefulness of cetylpyridinium chloride-containing mouthwashes in inhibiting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and reducing the risk of viral transmission. The study is published in the Journal of Medical Microbiology (2022). A scientific review, published in the  Journal of Formosan Medical Association  (2022) also concluded that mouthwash containing CPC shows potential fo...
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12 Best Natural Ozempic Alternatives 2025 (Resource Guide)

By Dr Frank Yap, MD
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If there's anything the Ozempic craze has taught us, it's that people are hungry for weight loss solutions. But as the world leans into wellness, many are now looking beyond pharmaceuticals, turning their gaze to nature's arsenal for blood sugar balance and metabolic health. The 2023 report from the World Obesity Federation estimates that the economic impact of overweight and obesity will surpass $4.3 trillion annually by 2035. In the U.S., the CDC  reports the prevalence of obesity in adults was 41.9% measured from 2017 to March 2020. This represented an increase from 30.5% from 1999 to 2000. The estimated annual medical costs were roughly $173 billion in 2019 dollars. The weight loss and weight management diet market size was valued at 192.2 billion in 2019, and is projected reach $295.3 billion by 2027, registering a CAGR of 7.0% from 2021 to 2027. ( source ) Prescriptions for semaglutide have doubled since mid-2021, rising to mor...
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7 Best Organic Vitamin D3 and K2 Supplements 2025

By Dr Frank Yap, MD
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In recent weeks and months, several publications and studies have suggested that maintaining adequate levels of vitamin D would seem potentially beneficial in fighting the COVID-19 infection. How do you know that your vitamin D level is adequate? Most people in the United States consume less than recommended amounts of vitamin D. An analysis of data from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 5.1 mcg (204 IU) in men, 4.2 mcg (168 IU) in women, and 4.9 mcg (196 IU) in children aged 2–19 years ( NHANES ). What Is Vitamin D? Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune syste...
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9 Best Calcium, Magnesium, Vitamin D3 and K2 Supplements 2025

By Dr Frank Yap, MD
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Calcium, magnesium, vitamin D and Vitamin K2 are vitamin and minerals that are vital to several bodily processes. Though they occur naturally in a variety of foods, many people take supplements to help increase their intake. Benefits and uses 1. May support bone health Calcium is the main mineral in your bones, which hold more than 99% of your body’s calcium stores. Your body is constantly regenerating its bone tissue, so it’s important to consume an adequate amount of this mineral daily ( bones.nih.gov ). Magnesium plays a key role in converting vitamin D into its active form, which aids calcium absorption ( Trusted Source ). Therefore, you can minimize your vitamin D requirement by making sure you’re also getting enough magnesium. Research has confirmed higher magnesium intake helps reduce your risk of vitamin D deficiency by activating more of it.  A  groundbreaking 2017 review  compiled over 80 studies that show vitamin D3 and K2 together might be greater than...
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12 Best Quercetin and Zinc Supplements of 2025

By Dr Frank Yap, MD
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Zinc is a powerful immune nutrient known for its benefits for providing immune health support and inflammation reduction as well as for improving cold and respiratory symptoms, wound healing, acne reduction, and lowering the risk of age-related diseases.  Quercetin has anti-inflammatory and antioxidant properties that can help combat various chronic diseases. In addition, quercetin is also a zinc ionophore that helps to transport zinc molecules into the cells. Therefore, quercetin and zinc in combination exerts a synergistic antiviral, anti-inflammatory and antioxidant properties.  What Is Quercetin? Quercetin is an antioxidant that belongs to a class of water-soluble plant substances called flavonoids, which are present in certain fruits and vegetables. According to  an article  in Current Research in Nutrition and Food Science, the bioavailability of quercetin absorbed by your body varies, depending on the source...
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How Your Diet Shapes the Way Your Skin Ages (2025)

By Dr Frank Yap, MD
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The skin is your body's largest organ, accounting for roughly 15% of your total body weight. It acts as the primary barrier between your internal systems and the external world, and reflects the cumulative impact of daily habits and internal physiology. Like every tissue in the body, the skin undergoes a natural aging process marked by gradual structural and cellular changes. 1 While this process unfolds over time, its pace and visibility are shaped by external influences. Among these, diet has emerged as a key factor with far-reaching effects on skin appearance and resilience. A recent review published in Food Science and Nutrition (2) explored this connection in depth. Drawing from research over the past five years, the authors examined how dietary habits and specific foods affect skin aging. Understanding Your Skin's Structure and Function Your skin is a layered defense system that gives protection from external threats, maintains internal stability, and participates in immu...
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9 Best Vitamin D3, K2 and Magnesium Supplements 2025

By Dr Frank Yap, MD
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Magnesium, vitamin D and Vitamin K2 are vitamin and minerals that are vital to several bodily processes. Though they occur naturally in a variety of foods, many people take supplements to help increase their intake. Magnesium, Vitamin D3 and Vitamin K Dosage The typical daily dosage recommendations for these nutrients are: Magnesium: 400–500 mg Vitamin D3: 800 IU (20 mcg)  Vitamin K : 120mcg Food With Magnesium, Vitamin D3 and Vitamin K Magnesium: dark chocolate, avocados, nuts, leafy vegetables, and legumes Vitamin D3: avocados, nuts, seeds, full-fat dairy products and eggs Vitamin K: turnips, spinach, kale, brocolli, soybeans, carrots, Chicken If you’re concerned you may be deficient in any of these nutrients, talk to a health professional who can test your levels and determine whether you should eat more of these foods or take a supplement. Benefits and uses 1. May support bone health Magnesium  plays a key role in converting vitamin D into its active form, which aids calci...
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Retatrutide vs Tirzepatide vs Semaglutide (Ozempic): What's the difference?

By Dr Frank Yap, MD
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Introduction The landscape of obesity treatment has evolved dramatically with the introduction of advanced medical therapeutics like retatrutide (RETA, LY3437943), tirzepatide, and semaglutide. These drugs, originally developed to manage type 2 diabetes, have shown remarkable efficacy in promoting weight loss, making them game-changers for obesity management. However, each drug has unique mechanisms, benefits, and potential applications, including emerging roles in cancer prevention. This article compares retatrutide, tirzepatide, and semaglutide, highlighting their differences in mechanism of action, weight loss efficacy, additional health benefits, and side effects to help patients and healthcare providers make informed decisions. Mechanism of Action Semaglutide : Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA). It mimics the action of GLP-1, a hormone that enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite. Mar...
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