Best Vitamin D3 and K2 Supplements: Reviews and Prices 2020 / 2021

In recent weeks and months, several publications and studies have suggested that maintaining adequate levels of vitamin D would seem potentially beneficial in fighting the COVID-19 infection. How do you know that your vitamin D level is adequate? Most people in the United States consume less than recommended amounts of vitamin D. An analysis of data from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 5.1 mcg (204 IU) in men, 4.2 mcg (168 IU) in women, and 4.9 mcg (196 IU) in children aged 2–19 years (NHANES).

What Is Vitamin D?

Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time.

Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune system needs vitamin D to fight off invading bacteria and viruses. Together with calcium, vitamin D also helps protect older adults from osteoporosis. Vitamin D is found in cells throughout the body.

There are two main dietary forms (NIH):
  • Vitamin D3 (cholecalciferol). Found in some animal foods, like fatty fish and egg yolks.
  • Vitamin D2 (ergocalciferol). Found in some plants, mushrooms, and yeasts.
Of the two, D3 (cholecalciferol) seems to be almost twice as effective at increasing blood levels of vitamin D as D2 (ergocalciferol) (NIHNIH).

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Best Vitamin D3 and K2 Supplement Brands in 2020

We have done our research and shortlisted the best for you. The list is based on recommendations by third party organizations, online reviews and popularity on search results and forums.

Here are the best vitamin D3 and K2 supplements that you can buy today.

1. Now Foods Vitamin D3 & K2 (120 Veg Caps)


Around $10.51 > Check Price on Amazon

More than 2,900 customer reviews and a 4.7 out of 5 overall rating on Amazon. As compared to the Sports Research Vitamin K2 and D3, the dose of the vitamin D3 and K2 are lower.
  • 1,000 IU / 45 mcg (D3 / K2) per veg capsule
  • Also has 3 mg of vitamin C per veg capsule
  • Supports Bone Health
  • Plus Cardiovascular Support
  • Non-GMO
  • Family Owned Since 1968
  • GMP Quality Assured

Editor's Note: Most of the Top 10 Vitamin D supplements as listed on the Amazon Best Sellers have dosages that exceed the maximum recommended dose (In USA and UK) of Vitamin D of 4,000 IU. Most of the brands also come in multiple dosages. Do check the label before you purchase.

2. Vitamin D by Nature’s Bounty for Immune Support


Price: $17.10 > Check Price on Amazon

More than 14,000 customer reviews and a 4.8 out of 5 overall rating on Amazon. #3 in Vitamin D Supplements of Amazon Best Sellers.
  • Immune support: 350-count, 2,000 IU Vitamin D3 Softgels for immune health. Vitamin D by Nature’s Bounty may assist the immune system by helping to regulate T and B-lymphocytes. Vitamin D3 is a more potent form of Vitamin D.
  • Strong, healthy bones: In addition to immune support, getting a sufficient amount of Vitamin D is critical to building and maintaining strong bones in adults. It is essential for calcium absorption to help support healthy bones. Nature’s Bounty Vitamin D3 Softgels supplement the Vitamin D your body needs for overall health.
  • Year-round support: Vitamin D3 supplements by Nature’s Bounty contain the same form of Vitamin D that is naturally formed in the body through exposure to sunshine. Nature’s Bounty Vitamin D3 helps replicate the benefits of natural sunshine all year long.
  • Purity is our priority: Nature’s Bounty is committed to safety and purity in all our supplements. Our rapid release Vitamin D3 Softgels are non-GMO, gluten- and sugar-free, and contain no artificial colors, or sweeteners.
  • From the trusted wellness experts: Nature’s Bounty Vitamin D supplements are a product of 50 years of dedication to quality, consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence.
Vitamin D by Nature's Bounty also come in various other dosages:

Most customers that purchased Vitamin D supplements on Amazon also bought this item: 
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Frequently Asked Questions

What Does Vitamin D Do in Your Body?

Vitamin D needs to undergo two conversion steps to become active (Trusted SourceTrusted Source).

First, it is converted to calcidiol, or 25(OH)D, in your liver. This is the storage form of the vitamin.

Second, it is converted to calcitriol, or 1,25(OH)2D, mostly in your kidneys. This is the active, steroid-hormone form of vitamin D.

Calcitriol interacts with the vitamin D receptor (VDR), which is found in almost every single cell in your body (Trusted SourceTrusted Source).

When the active form of vitamin D binds to this receptor, it turns genes on or off, leading to changes in your cells. This is similar to how most other steroid hormones work (Trusted SourceTrusted Source).

Vitamin D affects various cells related to bone health. For example, it promotes the absorption of calcium and phosphorus from your gut (Trusted Source).

But scientists have recently discovered that it also plays roles in other areas of health, such as immune function and protection against cancer (Source).

Vitamin D3 supplements appear to be more effective at raising vitamin D levels than D2 supplements. 

Vitamin D ensures that your blood levels of calcium are high enough to meet your body’s demands. However, vitamin D does not fully control where the calcium in your body ends up. That’s where vitamin K steps in. Vitamin K2 supplements have been proven to be more effective than vitamin K1. That's why most of the top vitamin D supplement brands do combine their vitamin D3 with K2.

Vitamin D and COVID Link

A study published in November 2020 from Singapore (CW Tan, Nutrition 2020), found that those who were started on a daily oral dose of vitamin D3 (1,000 IU), magnesium (150 mg) and vitamin B12 (500 mcg) within the first day of hospitalisation and continued up to 14 days were significantly less likely to require oxygen therapy and further intensive care.

The statement released on 2 October by the U.S. president’s physician said that in addition to the antibodies, Trump “has been taking zinc, vitamin D, famotidine, melatonin and a daily aspirin.”

Several publications and studies have suggested that maintaining adequate levels of vitamin D would seem potentially beneficial in fighting the COVID-19 infection.

A recent study, published in JAMA (JAMA Netw Open. 2020) found that persons who are likely to have deficient vitamin D levels at the time of COVID-19 testing were at substantially higher risk of testing positive for COVID-19 than were persons who were likely to have sufficient levels.

What is the Reference Daily Intake (RDI) for vitamin D?

The RDI for vitamin D is as follows (NIH):
  • 400 IU (10 mcg): infants, 0–12 months
  • 600 IU (15 mcg): children and adults, 1–70 years old
  • 800 IU (20 mcg): older adults and pregnant or breastfeeding women

What Helps Vitamin D Absorption?

Vitamin D is a fat-soluble vitamin, meaning that it does not dissolve in water and is absorbed best in your bloodstream when paired with high-fat foods.

For this reason, it’s recommended to take vitamin D supplements with a meal to enhance absorption.

According to one study in 17 people, taking vitamin D with the largest meal of the day increased vitamin D blood levels by about 50% after just 2–3 months (NIH).

In another study in 50 older adults, consuming vitamin D alongside a fat-heavy meal increased vitamin D blood levels by 32% after 12 hours compared to a fat-free meal (NIH).

Avocados, nuts, seeds, full-fat dairy products and eggs are nutritious sources of fat that help boost your vitamin D absorption.

What is the Best Vitamin D Foods?

Here is the vitamin D3 content of a few of the best food sources (NIH):
FoodAmount% RDI
Cod liver oil, 1 tablespoon (15 ml)1,360 IU / 34 mcg227%
Salmon, cooked, 3 ounces (85 grams)447 IU / 11 mcg75%
Tuna, canned in water, 3 ounces (85 grams)154 IU / 4 mcg26%
Beef liver, cooked, 3 ounces (85 grams)42 IU / 1 mcg7%
1 large whole egg (D is found in yolk)41 IU / 1 mcg7%
1 sardine, canned in oil, drained23 IU / 0.6 mcg4%
Although fatty fish like salmon, mackerel, swordfish, trout, tuna, and sardines are decent sources, you would have to eat them almost every day to get enough.

The only excellent dietary source of vitamin D is fish liver oil — such as cod liver oil — which contains upwards of two times the Reference Daily Intake (RDI) in a single tablespoon (15 ml).

Keep in mind that dairy products and cereals are often fortified with vitamin D (NIH).

Some rare mushrooms also harbor vitamin D, and egg yolks contain small amounts.



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