The Aesthetics Advisor

In recent years, it's become increasingly apparent that the composition of microbes in your gut — which is as distinct to you as your fingerprint — plays an enormous role in health and disease prevention. Your gut flora influences the function of various internal organs, such as your skin, lungs, breasts and liver. 1 For example, 2018 research 2  by the National Institute of Health shows gut microbes control antitumor immune responses in the liver, and that antibiotics — by depleting your gut of valuable bacteria — can alter the composition of immune cells in your liver and trigger tumor growth. Aside from cancer, dozens of other health conditions have been traced back to the influence of gut microbes as well, including obesity, depression, chronic fatigue syndrome, Parkinson's and allergies, 3  just to name a few. One of the reasons for this is because your gut is the main residence of your immune system. 4 Disrupt your gut microbiome and you automatically...

Abstract Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) — including semaglutide, tirzepatide, and liraglutide — are cornerstone therapies for type 2 diabetes (T2DM) and obesity. Recent trials and regulatory updates (including oral semaglutide) have expanded their therapeutic landscape. Objective: Systematically synthesize clinical evidence on GLP-1 RAs with updated 2025 data on metabolic outcomes, cardiovascular events, and safety. Methods: A PRISMA-aligned systematic review of Phase III RCTs, cardiovascular outcome trials (CVOTs), and high-quality meta-analyses was conducted. Data sources included PubMed/MEDLINE and recent literature through December 2025. Results: GLP-1 RAs consistently improve glycemic control (HbA1c reductions ~0.8–1.8%) and promote significant weight loss (up to ~20% with tirzepatide). Recent evidence supports reductions in MACE in high-risk patients and novel data on oral formulations. Safety profiles remain dominated by gastrointestinal...

Mitochondria, are the structures inside of your cells that produce about 90% of the energy generated in your body (1). This energy is necessary for cellular regeneration and detoxification, as well as muscle contraction and each biochemical cascade that occurs. In short, your cells require energy to function, and healthy mitochondria are critical to that energy supply. Mitochondria also play an important role in apoptosis, or programmed cell death, ensuring that malfunctioning cells die and are cleared from your system. In short, mitochondria are key to health and disease prevention. Without mitochondrial health, your well-being and longevity may suffer.   There are many strategies to optimize mitochondrial function. Eating right, timing your meals and exercising are among them. However, there are also mitochondria boosting supplements you can use strategically to support your mitochondria. Top options include the following. 1. Coenzyme Q10 (CoQ10) CoQ1...