Betadine (Povidone Iodine): COVID-19, Price and Reviews 2021

Povidone iodine (PVP-I) is an antiseptic that has been used for over 150 years. It is already proved that different concentration of PVP-I can deactivate COVID-19 virus. 

Betadine Iodine and COVID-19

Povidone Iodine COVID-19 Studies

We have compiled a list of povidone iodine COVID-19 studies below:

Feb 2021 - Guenezan et al., JAMA Otolaryngol Head Neck Surg., doi:10.1001/jamaoto.2020.5490 (Peer Reviewed)
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial
RCT of PCR+ patients with Ct<=20 with 12 treatment and 12 control patients, concluding that nasopharyngeal decolonization may reduce the carriage of infectious SARS-CoV-2 in adults with mild to moderate COVID-19. All patients but 1 had negative viral titer by day 3 (group not specified). There was no significant difference in viral RNA quantification over time. The mean relative difference in viral titers between baseline and day 1 was 75% [43%-95%] in the intervention group and 32% [10%-65%] in the control group. Thyroid dysfunction occurred in 42% of treated patients, with spontaneous resolution after the end of treatment. Patients in the treatment group were younger.

Dec 2020 - Choudhury et al., Bioresearch Communications, Volume 7, Issue 1, January 2021 (Peer Reviewed)
Effect of 1% Povidone Iodine Mouthwash/Gargle, Nasal and Eye Drop in COVID-19 patient
RCT 606 patients in Bangladesh for povidone iodine mouthwash/gargle, nasal drops and eye drops showing significantly lower death, hospitalization, and PCR+ at day 7.

Sep 2020 - Frank et al., JAMA Otolaryngol Head Neck Surg, doi:10.1001/jamaoto.2020.3053 (Peer Reviewed) (In Vitro)
In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2
In Vitro study showing povidone-iodine nasal antiseptics at concentrations (0.5%, 1.25%, and 2.5%) completely inactivated SARS-CoV-2 within 15 seconds of contact. No cytotoxic effects on cells were observed after contact with each of the nasal antiseptics tested.

Sep 2020 - Mohamed et al., medRxiv, doi:10.1101/2020.09.07.20180448 (Preprint)
Early viral cleerance among COVID-19 patients when gargling with povidone-iodine and essential oils: a pilot clinical trial
Tiny RCT with 5 PVP-I patients, gargling 30 seconds, 3x per day, and 5 control patients (essential oils and tap water were also tested), showing improved viral clearance with PVP-I.

June 2020 - Hassandarvish et al., Nature's British Dental Journal volume, doi:10.1038/s41415-020-1794-1 (Peer Reviewed) (In Vitro)
Povidone iodine gargle and mouthwash
In Vitro study showing undiluted PVP-I (1% w/v) achieved >5 log10 reduction in SARS-CoV-2 virus titres at 15, 30 and 60 seconds treatment exposure under both clean and dirty conditions. In contrast, when PVP-I was tested at 1:2 dilution a >4 log10 kill at 15 seconds and >5 log10 kill at 30 and 60 seconds in comparison to control was seen in both clean and dirty conditions.

Betadine Price and Reviews 2021


Betadine Sore throat Gargle (Amazon)


Betadine Antiseptic Sore Throat Gargle Price: $10

About this item
  • CONTAINS one 8 oz bottle (24 uses) of Betadine Antiseptic Sore Throat Gargle for the temporary relief of occasional sore throat
  • TREAT AND RELIEVE SORE THROAT SYMPTOMS the moment you feel a sore throat coming on
  • FAST ACTING GARGLE From Betadine, the brand that has been trusted by healthcare professionals for over 50 years.
  • 0.5% POVIDONE-IODINE ANTISEPTIC GARGLE
  • MINT FLAVOR, ALCOHOL FREE FORMULATION

Betadine Antiseptic Sore Throat Gargle Reviews:

4.6 out of 5 overall rating with more than 250 customer ratings.

Works well for sore throat - Reviewed in the United States on January 7, 2021
Recommended for people with covid19 coughing problems and flu and colds. Had a horrible sore throat from coughing heavily, and this helped sore throat get better after a few days of use.

Amazing stuff. Works great! - Reviewed in the United States on January 20, 2021
It works on covid sore throat. My mum being a seasoned pharmacist recommended this and asked me to add steam inhalation with the towel and hot water. I searched walgreens and cvs but all were out. I went online and Amazon sold it. I tried it and boy my throat just went quiet like 2 out ot 10 better instantly. No wonder it was out in stores. I have sore throat and headaches recovery, but the sore throat sucks. This helped.


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