Eating More Fruits and Vegetables May Extend Life Expectancy: Study

Fruits and vegetables are far more than fiber, carbohydrates, and protein. They’re complex synergies of vitamins, minerals, carotenoids, and polyphenols that can help us avoid the most prolific killers of our age. Research shows that fruits and vegetables can reduce the risk of chronic diseases, such as cardiovascular disease and cancer.



A research team led by Atsushi Goto, a professor at Yokohama City University, and Hitoshi Nakagama, president of the National Cancer Center Japan, conducted a 20-year research survey on the association between eating fruits and vegetables and all-cause mortality. The results, published in October 2022 in The Journal of Nutrition, an Oxford journal in the UK, show that people who consumed more vegetables and fruits had a 7 to 8 percent lower risk of death over 20 years, compared with those who consumed fewer vegetables and fruits.

European and American research had previously revealed that eating more fruits and vegetables can reduce the incidence of cardiovascular disease and the risk of all-cause mortality effectively, according to Goto. Yet the diet, lifestyle, and heredity of westerners are different from Asians. Thus, the research team selected 95,000 male and female volunteers, aged 40 to 69, from 11 Japanese prefectures and cities between 1990 and 1993, after excluding patients with cancer, cardiovascular disease, and liver disorders, for a long-term questionnaire survey.

Based on the results of the questionnaire, the researchers compiled statistics on the daily fruit and vegetable intake of the participants and divided them into five groups according to the amount of intake, from highest to lowest. The group with the lowest fruit and vegetable intake was the control group, which was compared to the other groups for subsequent risk of death from all-cause, cancer, and cardiovascular and respiratory diseases.

In 2018 (20 years later), the follow-up results show that the risk of all-cause death was reduced by 8 to 9 percent in the high fruits and vegetables intake group, while the risk of death for cardiovascular disease was reduced by approximately 9 percent.

The analysis of fruit intake shows that the risk of all-cause death was reduced by 8 percent in the highest intake group, and the risk of death by cardiovascular disease was decreased by 13 percent. It was particularly noticeable in women.

Analysis of vegetable intake shows that the group that consumed the most vegetables had a 7 percent lower risk of death than the group that consumed the least.

When mortality was analyzed separately for males and females, it was found that higher fruit intake in males was associated with lower respiratory mortality, while the same in females was associated with lower cardiovascular mortality.

According to the result of the analysis, the research team concluded that vegetables and fruits, which are rich in vitamins and dietary fiber, play an important role in people’s health. It’s recommended to intake more than 300 grams (10.5 ounces) of vegetables and more than 140 grams (5 ounces) of fruits daily.

“I hope this research result can provide data as a basic reference to the general public about the daily intake of fruits and vegetables,” Goto said.

Additionally, research on nearly 1.9 million people worldwide conducted by scientists from the Harvard T.H. Chan School of Public Health and other institutions also revealed that an appropriate amount of daily fruit and vegetable intake can extend life expectancy. The research results were published in the American medical journal Circulation in March 2021.

The research discovered that not all vegetables and fruits can reduce the risk of mortality. Starchy vegetables, such as peas, corn, and potatoes, and some fruit juices aren’t associated with lowering the risk of death from all-cause or certain chronic diseases.

Green leafy vegetables, such as spinach, lettuce, and kale; citrus fruits; berries; and carrots, which are rich in beta-carotene and vitamin C, have all shown benefits in reducing the risk of all-cause and cause-specific mortality.

How Vegetables Can Wreck Your Health

On the contrary, Sally Norton, author of “Toxic Superfoods: How Oxalate Overload Is Making You Sick — and How to Get Better,” reviews how and why even foods we’ve been told are healthy can wreak havoc on your health. As the title of the book implies, the main culprit in question is oxalate or oxalic acid, found in many plants, beans, grains, seeds and nuts, fruits, berries and herbs. (R)

So, just what are oxalates, why are they so bad, and how are they hidden in these superfoods that so many people are consuming? In short, it’s a naturally-occurring toxic, corrosive acid. In that state, it’s called oxalic acid. When the oxalic acid has minerals attached to it, it’s called oxalate.

Chemically, it’s a salt, and like other salts, it forms crystals that your body innately has a limited capacity to process. Calcium oxalate, for example, which is oxalic acid with calcium attached, forms into painful kidney stones.

And, unlike some other food-related toxins, oxalate cannot be removed by cooking, soaking or fermenting the food. You also cannot simply take a mineral supplement to address the depletion oxalates causes. 

Oxalic acid is a dicarboxylic acid, meaning it has two carbons and each carbon has an oxygen molecule attached to it. “This special carbolic acid has all kinds of damaging toxic powers when it’s near a membrane,” Norton says. She explains: 

“Membranes really matter to biochemistry and to our basic physiology at the cellular level. Your membranes have to have the right structure and the right materials in them to function well. You've been focusing lately on vegetable oils [linoleic acid] and how toxic they are.

It's messing up the structure of the membrane, because a membrane is this double layer of fatty acids. Well, it needs a certain structure to work.

Now, the membrane does all kinds of intellectual communication processes in the cell, helps the cell decide what to do next in any situation, and you need to have certain fatty acids only on the inside of the membrane. It's two layers. So, there's what we call the inner leaflet and the outer leaflet.

On the inner leaflet, there is a phospholipid called phosphatidylserine ... What's getting into your body and causing trouble is the free oxalic acid ion, this single little molecule that easily transverses your gut because it just floats in the water between the cells. We call that paracellular trans ...

When oxalate's around, it causes membrane damage to the point where that innate structure where the phosphatidylserine is now showing up on the outside of the membrane. That's bad news. For many cells, that means the cell is now in line to be removed because it's damaged. It's a signal to the immune system, hey, take away the cell. It's been harmed.

So, you lose your structured membrane. That creates all kinds of headaches for a cell. Often it cannot function properly. This is especially true of the cells that line the vascular system. So, the endothelial lining that is this giant organ of physiology, metabolism and maintenance of the body can be in trouble after, say, a spinach smoothie.”

The top three vegetable “superfoods” that are very high in oxalate and may cause trouble are spinach, Swiss chard and beet greens. Another high-oxalate food is almonds, which you can easily “overdose” on if you’re eating bread made with almond flour or drinking almond milk, or if you’re on a keto or paleo diet, as they both tend to rely heavily on almonds. Dark chocolate is another food that scores high for oxalates.

The Antidote to Oxalate

The good news is there’s an “antidote” to oxalate that can be helpful if you’re struggling with oxalate toxicity or just happened to eat a high-oxalate meal. That antidote is citrate e.g. magnesium citrate, calcium citrate and potassium citrate, typically to be taken with meals. This way absorption of any oxalate in the meal will be impaired. (R)

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