Medical Specialist News: Skin Specialists in Singapore | Dermatologists Singapore

By Dr Frank Yap, MD -
Medical Specialist News: Skin Specialists in Singapore | Dermatologists Singapore

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12 Best Natural Ozempic Alternatives 2025 (Resource Guide)

By Dr Frank Yap, MD -
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If there's anything the Ozempic craze has taught us, it's that people are hungry for weight loss solutions. But as the world leans into wellness, many are now looking beyond pharmaceuticals, turning their gaze to nature's arsenal for blood sugar balance and metabolic health. The 2023 report from the World Obesity Federation estimates that the economic impact of overweight and obesity will surpass $4.3 trillion annually by 2035. In the U.S., the CDC  reports the prevalence of obesity in adults was 41.9% measured from 2017 to March 2020. This represented an increase from 30.5% from 1999 to 2000. The estimated annual medical costs were roughly $173 billion in 2019 dollars. The weight loss and weight management diet market size was valued at 192.2 billion in 2019, and is projected reach $295.3 billion by 2027, registering a CAGR of 7.0% from 2021 to 2027. ( source ) Prescriptions for semaglutide have doubled since mid-2021, rising to mor...
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8 Best Vitamin D3 and K2 Supplements 2025: Benefits, Reviews and Prices

By Dr Frank Yap, MD -
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Most people in the United States consume less than recommended amounts of vitamin D . An analysis of data from the 2017–2018 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 4.3 mcg in men, 3.8 mcg in women, and 5 mcg (200 IU) in children aged 2–19 years ( NHANES 2017 - 2018 ). What Is Vitamin D? Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune system needs vitamin D to fight off invading bacteria and viruses. Together with calcium, vitamin D also helps protect older adults from osteoporosis. Vitamin D is found in cells throughout the body. Vitamin D Market Size The Global Vitamin D Market size was ...
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Retatrutide vs Tirzepatide vs Semaglutide (Ozempic): What's the difference?

By Dr Frank Yap, MD -
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Introduction The landscape of obesity treatment has evolved dramatically with the introduction of advanced medical therapeutics like retatrutide (RETA, LY3437943), tirzepatide (Mounjaro), and semaglutide (Ozempic). These drugs, originally developed to manage type 2 diabetes, have shown remarkable efficacy in promoting weight loss, making them game-changers for obesity management. However, each drug has unique mechanisms, benefits, and potential applications, including emerging roles in cancer prevention. This article compares retatrutide, tirzepatide, and semaglutide, highlighting their differences in mechanism of action, weight loss efficacy, additional health benefits, and side effects to help patients and healthcare providers make informed decisions. Credit: GoodRx Health Mechanism of Action Semaglutide : Semaglutide (Ozempic and Wegovy) is a glucagon-like peptide-1 receptor agonist (GLP-1 RA). It mimics the action of GLP-1, a hormone that enhances insulin secretion, suppresses glu...
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7 Best Organic Vitamin D3 and K2 Supplements 2025

By Dr Frank Yap, MD -
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In recent weeks and months, several publications and studies have suggested that maintaining adequate levels of vitamin D would seem potentially beneficial in fighting the COVID-19 infection. How do you know that your vitamin D level is adequate? Most people in the United States consume less than recommended amounts of vitamin D. An analysis of data from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 5.1 mcg (204 IU) in men, 4.2 mcg (168 IU) in women, and 4.9 mcg (196 IU) in children aged 2–19 years ( NHANES ). What Is Vitamin D? Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune syste...
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9 Best Vitamin D3, K2 and Magnesium Supplements 2025

By Dr Frank Yap, MD -
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Magnesium, vitamin D and Vitamin K2 are vitamin and minerals that are vital to several bodily processes. Though they occur naturally in a variety of foods, many people take supplements to help increase their intake. Magnesium, Vitamin D3 and Vitamin K Dosage The typical daily dosage recommendations for these nutrients are: Magnesium: 400–500 mg Vitamin D3: 800 IU (20 mcg)  Vitamin K : 120mcg Food With Magnesium, Vitamin D3 and Vitamin K Magnesium: dark chocolate, avocados, nuts, leafy vegetables, and legumes Vitamin D3: avocados, nuts, seeds, full-fat dairy products and eggs Vitamin K: turnips, spinach, kale, brocolli, soybeans, carrots, Chicken If you’re concerned you may be deficient in any of these nutrients, talk to a health professional who can test your levels and determine whether you should eat more of these foods or take a supplement. Benefits and uses 1. May support bone health Magnesium  plays a key role in converting vitamin D into its active form, which aids calci...
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Omega-3 101 — A Simple Way to Lower Your Risk of Disease

By Dr Frank Yap, MD -
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A few years ago,  William (Bill) Harris, Ph.D  founded the Fatty Acid Research Institute (FARI) 1   in South Dakota, which specializes in epidemiological research, where they look at the relationship between blood omega-3 levels and risk for disease. He's also a faculty member of the University of South Dakota School of Medicine. "We're trying to build a case that omega-3 levels in the blood are as, if not more, important than knowing your cholesterol level when it comes to your health and being able to control it,"  he says. Update: A  2024 study  published in BMJ Medicine suggests that regular use of fish oil may contribute to atrial fibrillation and stroke among the general population. The Omega-3 Index What he's referring to is the level of omega-3 in your red blood cell membranes. Two decades ago, his team developed a red blood cell membrane-based omega-3 test called the Omega-3 Index. You can take the  Omega-...
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Healthcare AI: In the ‘Wild West’ of AI Health Care, These 4 Things Could Go Very Wrong

By Dr Frank Yap, MD -
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Artificial intelligence (AI) is making headlines, and the reviews are mixed. Though the United States leads the world in AI investment, Americans remain skeptical. According to a global survey ( pdf ) by Ipsos, “Only 35 percent of sampled Americans agreed that products and services using AI had more benefits than drawbacks.” Among surveyed countries, the United States had one of the lowest percentages of those who agreed with the statement. Private industry has edged out academia in producing state-of-the-art AI systems; at the same time, the number of incidents of  ethical misuse of AI  has increased dramatically—from 10 in 2012 to more than 250 in 2021. The field is growing in what could be called a “Wild West” of AI. According to Stanford University’s  AI Index Report , “AI has moved into its era of deployment; throughout 2022 and the beginning of 2023, new large-scale AI models have been released every month.” These models include Stable Diffusion, Whisper, DALL-E 2, ...
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9 Best Calcium, Magnesium, Vitamin D3 and K2 Supplements 2025

By Dr Frank Yap, MD -
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Calcium, magnesium, vitamin D and Vitamin K2 are vitamin and minerals that are vital to several bodily processes. Though they occur naturally in a variety of foods, many people take supplements to help increase their intake. Benefits and uses 1. May support bone health Calcium is the main mineral in your bones, which hold more than 99% of your body’s calcium stores. Your body is constantly regenerating its bone tissue, so it’s important to consume an adequate amount of this mineral daily ( bones.nih.gov ). Magnesium plays a key role in converting vitamin D into its active form, which aids calcium absorption ( Trusted Source ). Therefore, you can minimize your vitamin D requirement by making sure you’re also getting enough magnesium. Research has confirmed higher magnesium intake helps reduce your risk of vitamin D deficiency by activating more of it.  A  groundbreaking 2017 review  compiled over 80 studies that show vitamin D3 and K2 together might be greater than...
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Economic Impact of Obesity to Surpass $4 Trillion by 2035

By Dr Frank Yap, MD -
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In 1954, obesity was called a common physical abnormality.(1) Today it's called an epidemic.(2) Many of the complications related to obesity are health conditions that negatively impact quality of life and increase health costs. These include lung, liver and heart diseases, arthritis and gout.(3) The 2023 report 4  from the World Obesity Federation estimates that the economic impact of overweight and obesity will surpass $4.3 trillion annually by 2035. In the U.S., the CDC 5  reports the prevalence of obesity in adults was 41.9% measured from 2017 to March 2020. This represented an increase from 30.5% from 1999 to 2000. The estimated annual medical costs were roughly $173 billion in 2019 dollars. Using this estimate, medical costs for obese adults were $1,861 higher than those who had a healthy weight. In children and adolescents 6  aged 2 to 19 years from 2017 to 2020, the prevalence of obesity was 19.7%, which in raw numbers was approximately 14.7 million adolescents an...
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Can Vitamin D and Magnesium Curb Your Anxiety and Depression?

By Dr Frank Yap, MD -
The use of magnesium and vitamin D for anxiety and depression has been trending on social media — and this is one viral theme that’s worth paying attention to. The chatter includes anecdotal reports from long-time anxiety sufferers who say they’ve gotten relief from the natural supplements. TikTok user Tyler Wesley, Fox News reported, posted video saying he takes 500 milligrams of magnesium and a dose of vitamin D daily, and it’s eliminated his anxiety symptoms. “I don’t have anxiety anymore. Thirty years, anxiety my whole life — I don’t have it anymore,” he wrote. 1  But this isn’t just hearsay. A wealth of research supports the use of magnesium and vitamin D to boost mental health. Is Your Mental Health Suffering From Not Enough Magnesium? Magnesium is necessary for the healthy functioning of most cells, especially your heart, kidneys and muscles. It’s involved in the functioning of more than 300 enzymes, 2  and low levels of magnesium impede cellular metabolic function and...
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