Reviews on skin specialists in Malaysia

By Dr Frank Yap, MD -
Reviews on skin specialists in Malaysia

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Ivermectin and Fenbendazole in the Treatment of Psoriasis? A Case Series of 13 Patients (2025)

By Dr Frank Yap, MD -
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Abstract Psoriasis is a chronic autoimmune condition affecting approximately 7.5 million individuals in the United States, with significant economic, physical, and psychological burdens. This case series reports on 13 patients who experienced notable improvements in psoriasis symptoms following treatment with ivermectin and/or fenbendazole, antiparasitic agents repurposed for this indication. Cases were derived from self-reported testimonials shared on social media platforms. Treatment durations ranged from 3 days to 3 months, with dosages varying between 6 mg ivermectin twice daily and combinations with fenbendazole. Rapid resolution of skin lesions was observed in most cases, with some achieving near-complete clearance. While these anecdotal reports suggest potential therapeutic efficacy, controlled clinical trials are warranted to validate these findings and elucidate underlying mechanisms. Introduction Psoriasis is a chronic inflammatory disorder characterized by hyperproliferation...
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7 Best Cetylpyridinium Chloride Mouthwash Brands 2025

By Dr Frank Yap, MD -
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A meta-analysis of 3 studies (C19early 2025) concluded that CPC (CetylPyridinium Chloride) may significantly lower risk with  viral clearance . One study shows significant benefit. Meta analysis using the most serious outcome reported shows 83% [6‑97%] lower risk . Results are consistent with early treatment being more effective than late treatment. A study, published in Nature ( Takeda 2022 ) concluded that CPC (CetylPyridinium Chloride) may inhibit SARS-CoV-2 infection even at lower concentrations. Another team of international scientists has also demonstrated the usefulness of cetylpyridinium chloride-containing mouthwashes in inhibiting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and reducing the risk of viral transmission. The study is published in the Journal of Medical Microbiology (2022). A scientific review, published in the  Journal of Formosan Medical Association  (2022) also concluded that mouthwash containing CPC shows potential fo...
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17 Best Natural Ozempic Alternatives 2025 (Resource Guide)

By Dr Frank Yap, MD -
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Some of the best natural alternatives to Ozempic include berberine, a supplement that has shown potential in managing blood sugar and promoting weight loss, often referred to as “nature’s Ozempic” in wellness communities. High-fiber foods also play a crucial role by helping to control appetite and improve metabolic health. Other natural options include psyllium husk, which provides soluble fiber supporting satiety and digestive health, and curcumin, known for its anti-inflammatory properties, which may aid metabolic balance. Additionally, green tea extract, magnesium, protein-rich foods, and lifestyle factors like adequate sleep and stress reduction contribute to weight management.  However, none of these natural alternatives are as potent or fast-acting as Ozempic itself, and their effects can vary widely among individuals. It is important to consult a healthcare provider before starting any supplement regimen, especially for managing blood sugar or weight loss. The 2023 rep...
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8 Best Vitamin D3 and K2 Supplements 2025: Benefits, Reviews and Prices

By Dr Frank Yap, MD -
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Most people in the United States consume less than recommended amounts of vitamin D . An analysis of data from the 2017–2018 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 4.3 mcg in men, 3.8 mcg in women, and 5 mcg (200 IU) in children aged 2–19 years ( NHANES 2017 - 2018 ). What Is Vitamin D? Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune system needs vitamin D to fight off invading bacteria and viruses. Together with calcium, vitamin D also helps protect older adults from osteoporosis. Vitamin D is found in cells throughout the body. Vitamin D Market Size The Global Vitamin D Market size was ...
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Hydroxychloroquine, Azithromycin and Zinc: Dosage, Z Pak and Zelenko Protocol for COVID-19 (2023)

By Dr Frank Yap, MD -
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As of January 2023, there are  more than 2,000 studies  published related to the treatment and prevention of COVID-19. As of January 2023, there are more than 350 published evidence of hydroxychloroquine for COVID-19 ( c19hcq.org ). As of January 2023, there are 38 published evidence of zinc for COVID-19 ( c19early.org/z ). In 2020, Hydroxychloroquine was touted as the most controversial drug in the world. Is there any new evidence to confirm or to disprove previous evidence? Hydroxychloroquine, Zinc and Azithromycin are among the handful of COVID-19 treatments that are being studied as potential candidates that might influence the outcome in the prevention and management of COVID-19.  Who makes hydroxychloroquine? Hydroxychloroquine (generic or scientific name) comes in various brand names. Plaquenil is a brand name of hydroxychloroquine from Sanofi.  Who makes azitromycin? Azithromycin (scientific name) comes in various brand names as well. Zithromax (from Pfizer),...
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Fotona 5D vs 4D vs Ultherapy (HIFU) vs Thermage: What Are the Differences?

By Dr Frank Yap, MD -
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If you are considering a non-surgical facelift treatment, you've come to the right place. The number of options for non-surgical facelifts have increased drastically in recent years, thus making it a struggle to decide which treatment would be best for you. This guide is here to help. What is a Non-Surgical Facelift? A non-surgical face-lift can include a number of different treatments and procedures that aim to address the effects of aging. Non-surgical options for facelifts fall into three categories: replenishing lost volume, resurfacing the superficial skin and tightening deeper tissue. Generally, a range of treatments are used in combination to achieve your overall facial rejuvenation goals. There are 3 different categories of non-surgical face lifts that can achieve lifting without plastic surgery:  Energy-based Filler-based Thread lift-based The energy based category is the biggest group with various technologies and jargons, thus could be overwhelming and confusing for you ...
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7 Best Organic Vitamin D3 and K2 Supplements 2025

By Dr Frank Yap, MD -
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In recent weeks and months, several publications and studies have suggested that maintaining adequate levels of vitamin D would seem potentially beneficial in fighting the COVID-19 infection. How do you know that your vitamin D level is adequate? Most people in the United States consume less than recommended amounts of vitamin D. An analysis of data from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) found that average daily vitamin D intakes from foods and beverages were 5.1 mcg (204 IU) in men, 4.2 mcg (168 IU) in women, and 4.9 mcg (196 IU) in children aged 2–19 years ( NHANES ). What Is Vitamin D? Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Vitamin D is important to the body in many ways. It helps the body absorb calcium from food and supplements. Muscles need it to move, for example, nerves need it to carry messages between the brain and every body part, and the immune syste...
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9 Best Vitamin D3, K2 and Magnesium Supplements 2025

By Dr Frank Yap, MD -
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Magnesium, vitamin D and Vitamin K2 are vitamin and minerals that are vital to several bodily processes. Though they occur naturally in a variety of foods, many people take supplements to help increase their intake. Magnesium, Vitamin D3 and Vitamin K Dosage The typical daily dosage recommendations for these nutrients are: Magnesium: 400–500 mg Vitamin D3: 800 IU (20 mcg)  Vitamin K : 120mcg Food With Magnesium, Vitamin D3 and Vitamin K Magnesium: dark chocolate, avocados, nuts, leafy vegetables, and legumes Vitamin D3: avocados, nuts, seeds, full-fat dairy products and eggs Vitamin K: turnips, spinach, kale, brocolli, soybeans, carrots, Chicken If you’re concerned you may be deficient in any of these nutrients, talk to a health professional who can test your levels and determine whether you should eat more of these foods or take a supplement. Benefits and uses 1. May support bone health Magnesium  plays a key role in converting vitamin D into its active form, which aids calci...
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10 Best Supplements for Mitochondrial Health 2025

By Dr Frank Yap, MD -
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Mitochondria, are the structures inside of your cells that produce about 90% of the energy generated in your body (1). This energy is necessary for cellular regeneration and detoxification, as well as muscle contraction and each biochemical cascade that occurs. In short, your cells require energy to function, and healthy mitochondria are critical to that energy supply. Mitochondria also play an important role in apoptosis, or programmed cell death, ensuring that malfunctioning cells die and are cleared from your system. In short, mitochondria are key to health and disease prevention. Without mitochondrial health, your well-being and longevity may suffer.   There are many strategies to optimize mitochondrial function. Eating right, timing your meals and exercising are among them. However, there are also mitochondria boosting supplements you can use strategically to support your mitochondria. Top options include the following. 1. Coenzyme Q10 (CoQ10) CoQ1...
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GLP-1 Receptor Agonists in Metabolic Disease: A 2025 PRISMA-Guided Systematic Review of Efficacy, Safety, and Comparative Effectiveness

By Dr Frank Yap, MD -
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Abstract Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) — including semaglutide, tirzepatide, and liraglutide — are cornerstone therapies for type 2 diabetes (T2DM) and obesity. Recent trials and regulatory updates (including oral semaglutide) have expanded their therapeutic landscape. Objective: Systematically synthesize clinical evidence on GLP-1 RAs with updated 2025 data on metabolic outcomes, cardiovascular events, and safety. Methods: A PRISMA-aligned systematic review of Phase III RCTs, cardiovascular outcome trials (CVOTs), and high-quality meta-analyses was conducted. Data sources included PubMed/MEDLINE and recent literature through December 2025. Results: GLP-1 RAs consistently improve glycemic control (HbA1c reductions ~0.8–1.8%) and promote significant weight loss (up to ~20% with tirzepatide). Recent evidence supports reductions in MACE in high-risk patients and novel data on oral formulations. Safety profiles remain dominated by gastrointestinal...
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