Fluvoxamine and Ivermectin: Early treatment for COVID-19 is key to better outcomes
According to Steve Kirsch, Executive Director of the COVID-19 Early Treatment Fund which funded the clinical trials in the US of fluvoxamine:
Ivermectin is an anti-parasitic medication widely used in low- and middle-income countries to treat parasitic worm infections in adults and children. It’s been used for decades for this purpose by over 3.7 billion people, and is considered safe and effective. It has an increasing list of indications due to its antiviral and anti-inflammatory properties, and is included on the WHO’s Model List of Essential Medicines.
We don't think the trial was gamed at all. I think this was a legit result.
We know the Principal Investigator Edward Mills and believe he is totally honest and we have no reason not to believe the results he obtained. But we also believe other researchers as well.
So the question everyone has is how could these drugs do so well in other studies?
The answer: the variant was different. P1 is the variant in Brazil and makes Delta look like a walk in the park. If you do not treat P1, instantly upon symptoms, you will see big failures.
Had fluvoxamine been given on Day 0 instead of Day 4, there would have been a dramatically different result.
Had ivermectin been dosed at 0.6mg/day for 14 days starting on Day 0 (the first day of symptoms), there would have been a dramatically different result.
The more aggressive the variant, the earlier and harder you have to treat it.
Ivermectin likely failed for these four reasons:
- too little a dose
- started too late
- not continued for long enough
- many patients may have already been taking ivermectin
Also, you can't treat Delta and P1 in the hospital... it is much much tougher there. It's like a fire department arriving when the entire building is in flames.
The recommendations below are based on both scientific studies and the experience of clinicians in treating COVID-19.
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