Nattokinase vs Nattozimes: What's the Difference?

Nattokinase and Nattozimes are two supplements that are often marketed for their ability to support cardiovascular health. While they share similarities in name and origin, there are key differences between these two supplements that consumers should be aware of when considering which one to take.

What is Nattokinase?

Nattokinase is an enzyme that is derived from the Japanese fermented soybean dish called natto. Natto has been a traditional food in Japan for over a thousand years and is made by fermenting soybeans with a specific strain of bacteria called Bacillus subtilis natto.

Nattokinase is produced during the fermentation process and is known for its ability to break down fibrin, a protein that is involved in blood clotting. This is why nattokinase is often marketed as a supplement that can help support cardiovascular health by reducing the risk of blood clots, to help lower cholesterol, reduce inflammation, and improve circulation. 

Nattokinase for Blood Clots

Nattokinase dissolves blood clots by directly hydrolyzing fibrin and plasmin substrate. It converts endogenous prourokinase to urokinase (uPA). It also degrades plasminogen activator inhibitor (PAI-1) and increases the level of tissue plasminogen activator (t-PA). (Source)

Furthermore, a study has also suggests that daily NK supplementation is an effective way to manage the progression of atherosclerosis and potentially may be a better alternative to statins which are commonly used to reduce atherosclerosis and further to prevent cardiovascular attack and stroke in patients.

In this clinical study (Chen 2022) involving 1,062 participants, the objective was to examine the efficacy of NK (nattokinase) in atherosclerosis and hyperlipidemia and safety at the dose of 10,800 FU/day after 12 months of oral administration. 

Authors found that NK at a dose of 10,800 FU/day effectively managed the progression of atherosclerosis and hyperlipidemia with a significant improvement in the lipid profile. The lipid-lowering effect of NK was more prominent in subjects who smoked, drank alcohol, and subjects with higher BMI. Regular exercise further improved the effects of NK. 

Co-administration of vitamin K2 and aspirin with NK produced a synergetic effect. In conclusion, the data demonstrate that atherosclerosis progression and hyperlipidemia can be effectively managed with NK at a dose of 10,800 FU/day. The lower dose of 3,600 FU per day is ineffective. Some lifestyle factors and the coadministration of vitamin K2 and aspirin lead to improved outcomes in the use of NK. The findings provide clinical evidence on the effective dose of NK in the management of cardiovascular disease and challenge the recommended dose of 2,000 FU per day.

Tanikawa et al. (2022) examined the effect of nattokinase on the COVID-19 spike protein. In the first experiment, they demonstrated that spike was degraded in a time and dose-dependent manner in a cell lysate preparation that could be similar to a vaccine recipient. The second experiment demonstrated that nattokinase degraded the spike protein in SARS-CoV-2 infected cells. This was reproduced in a similar study done by Oba and colleagues in 2021.

Nattokinase is typically sold as a dietary supplement in capsule form, with recommended dosages ranging from 1000 to 2000 fibrinolytic units (FU) per day. It is important to note that nattokinase should not be taken by individuals who are taking blood thinners or who have a bleeding disorder, as it can increase the risk of bleeding.

What are Nattozimes?

Nattozimes, on the other hand, are a blend of enzymes that are designed to mimic the fibrinolytic activity of nattokinase. Nattozimes are often marketed as an alternative to nattokinase for individuals who may be sensitive to soy or who are looking for a more concentrated source of fibrinolytic enzymes.

Nattozimes typically contain a combination of enzymes, including nattokinase, serrapeptase, and protease. Serrapeptase is another enzyme that is known for its fibrinolytic activity, while protease is a general term for a group of enzymes that break down proteins into smaller peptides and amino acids.

Nattozimes are sold in capsule form, with recommended dosages varying depending on the specific product. Like nattokinase, individuals who are taking blood thinners or who have a bleeding disorder should not take nattozimes without consulting with their healthcare provider first.

What are the key differences between Nattokinase and Nattozimes?

Nattozimes vs nattokinase? While nattokinase and nattozimes are both marketed as supplements that can support cardiovascular health, there are key differences between these two products that consumers should be aware of.

First and foremost, nattokinase is a single enzyme that is derived from the fermentation of soybeans, while nattozimes are a blend of enzymes that may or may not include nattokinase.

Secondly, nattokinase is typically sold as a standalone supplement, while nattozimes are often marketed as a combination supplement that contains multiple fibrinolytic enzymes.

Finally, nattokinase is derived from soybeans and may not be suitable for individuals who are sensitive to soy, while nattozimes may be a better option for these individuals as they do not contain soy.

Which supplement is right for me?

Deciding whether to take nattokinase or nattozimes will depend on your individual health needs and preferences. If you are looking for a single enzyme supplement that is derived from a traditional food source and has a long history of use in Japan, nattokinase may be the right choice for you.

On the other hand, if you are looking for a blend of enzymes that may be more concentrated and may not contain soy, nattozimes may be a better option. It is important to note that both of these supplements should be taken under the guidance of a healthcare provider, especially if you are taking any other medications or have any underlying health conditions.

Individuals who are interested in taking nattokinase should consider whether they have any sensitivity to soy or soy-based products, as nattokinase is derived from fermented soybeans. Additionally, individuals who are looking for a specific enzyme supplement that has been used for centuries in traditional Japanese medicine may prefer nattokinase over nattozimes.

On the other hand, individuals who are looking for a blend of enzymes that may be more concentrated and may not contain soy may prefer nattozimes. Nattozimes typically contain a combination of enzymes, including nattokinase, serrapeptase, and protease, which may offer additional health benefits beyond those of nattokinase alone.

Ultimately, the decision between nattokinase and nattozimes will depend on an individual's specific health needs and preferences. It is important to consult with a healthcare provider before taking either of these supplements, especially if you are taking any other medications or have any underlying health conditions. Your healthcare provider can help you determine which supplement, if any, is right for you and can provide guidance on proper dosages and potential interactions with other medications or supplements you may be taking.

Conclusion

In conclusion, while nattokinase and nattozimes are both supplements that are marketed for their ability to support cardiovascular health, there are key differences between these two products. Nattokinase is a single enzyme that is derived from the fermentation of soybeans, while nattozimes are a blend of enzymes that may or may not include nattokinase. Additionally, nattozimes may be a better option for individuals who are sensitive to soy or who are looking for a more concentrated source of fibrinolytic enzymes. Ultimately, the choice between these two supplements will depend on an individual's health needs and preferences, and it is important to consult with a healthcare provider before taking either of these supplements.

The Wellness Company’s Spike Support Formula

The Wellness Company's acclaimed Spike Support Formula contains scientifically-researched ingredients, including nattokinase, black seed oil (Nigella Sativa), green tea extract (EGCG) and selenium.

These ingredients are known for their ability to dissolve spike protein, prevent it from binding to cells, and repair tissue.

Recommended to maintain daily health for anyone exposed to COVID, vaccines, or shedding – and may help your body repair itself and remain at optimal health.

Where to buy Spike Support Formula: Spike Support Formula is available on The Wellness Company's website. Here is the link: Spike Support Formula (Long Haul Formula)

Note: To get 10% OFF, please use this coupon code: ONEDAYMD


Related: 


Best Supplements for CardioVascular Health

Comments

Labels

Show more

Popular posts from this blog

10 Best Vitamin C Serums Recommended by Dermatologists 2024

10 Best Vitamin C Serums for Brighter Skin 2024

8 Best Vitamin C Serums for Hyperpigmentation 2024

10 Best Cosmeceutical Ingredients of 2024

10 Best Natural Ozempic Alternatives 2024

Best Hair, Skin and Nail Supplements 2024: Do They Work?

12 Best Vitamin C Supplements 2024: Reviews and Prices

19 Most Important Supplements to Take - Dr Joseph Mercola

Best 10 Supplements Exploding in Popularity for 2024

13 Most Common Nutrient Deficiencies (2023)

Archive

Show more