Effect of 1% Povidone Iodine Mouthwash/Gargle, Nasal and Eye Drop in COVID-19 patient

By Dr Frank Yap, MD -

Background: The sudden onset of COVID-19 began in late 2019 caused by a novel coronavirus (SARS-COV2) and on 11th March, WHO declared it to have developed pandemic status. There is still no specific treatment and vaccine available for COVID-19; causing wide spread health problem and concern of the globe. Povidone iodine (PVP-I) is an antiseptic that has been used for over 150 years. It is already proved that different concentration of PVP-I can deactivate COVID-19 virus.

Methodology: In this randomized controlled clinical trial, out of 1113 patients 606 patients were enrolled and divided in 2 groups by randomization after taken consents. In Gr-A, 303 patients underwent mouthwash/gargle, nasal drops and eye drops with 1% povidone iodine 4 hourly for 4 weeks as well as symptomatic treatment according to need. In Gr-B 303 patients were advised mouthwash/gargle, nasal cavity and eye wash with lukewarm water 4 hourly for 4 weeks and symptomatic treatment according to need. RT-PCR test done every 3rd, 5th and 7th day and Thyroid hormone level (TSH,T3, T4, FT4) at 4th week for follow up.

Results: The group of patients used 1% PVP-I have shown tremendously reduced mortality, morbidity and hospital as well as financial burden in this covid situation.

Conclusion: Administration of 1% PVP-I as mouthwash/gargle, nasal or eye drop is simple, rapid and cost effective in reduction of mortality and morbidity by COVID-19.


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Betadine Price and Reviews 2021


Betadine Sore throat Gargle (Amazon)

Betadine Antiseptic Sore Throat Gargle Price: $10

About this item
  • CONTAINS one 8 oz bottle (24 uses) of Betadine Antiseptic Sore Throat Gargle for the temporary relief of occasional sore throat
  • TREAT AND RELIEVE SORE THROAT SYMPTOMS the moment you feel a sore throat coming on
  • FAST ACTING GARGLE From Betadine, the brand that has been trusted by healthcare professionals for over 50 years.
  • 0.5% POVIDONE-IODINE ANTISEPTIC GARGLE
  • MINT FLAVOR, ALCOHOL FREE FORMULATION

Betadine Antiseptic Sore Throat Gargle Reviews:

4.6 out of 5 overall rating with more than 250 customer ratings.

Works well for sore throat - Reviewed in the United States on January 7, 2021
Recommended for people with covid19 coughing problems and flu and colds. Had a horrible sore throat from coughing heavily, and this helped sore throat get better after a few days of use.

Amazing stuff. Works great! - Reviewed in the United States on January 20, 2021
It works on covid sore throat. My mum being a seasoned pharmacist recommended this and asked me to add steam inhalation with the towel and hot water. I searched walgreens and cvs but all were out. I went online and Amazon sold it. I tried it and boy my throat just went quiet like 2 out ot 10 better instantly. No wonder it was out in stores. I have sore throat and headaches recovery, but the sore throat sucks. This helped.


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