Vladimir Zelenko Protocol: Prophylactic and Treatment Protocol for COVID-19 (updated May 2021)

A retrospective study analyzing Dr Zelenko's patient data was accepted for publication after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence.


This webpage compiles content related to the early outpatient treatment protocol that has been proposed by Dr. Vladimir Zelenko for the SARS-CoV-2 virus. Dr. Zelenko originally risk-stratified patients and treated high-risk patients with hydroxychloroquine, zinc, and azithromycin. 

He has since evolved his protocols to include a quercetin protocol for low-risk patients as well as guidelines for prophylaxis. Dr. Zelenko shared the details of his protocol on March and April 2020 in open letters to the medical community and also shared updated treatment and prophylaxis protocols on August 2020. 

He has also published his first research paper on his treatment protocol. See the press release. Dr. Zelenko's paper establishes, with statistical significance, that his early outpatient protocol reduces hospitalizations by 84%. Dr. Zelenko's statement to the U.S. Senate Committee on Homeland Secutity indicates no deaths from amongst the group of patients that initiated treatment during the first 4 days, and took medications for at least 5 days. 

Based on rapidly emerging clinical trials evidence of ivermectin, an anti-parasitic medicine, has highly potent real-world, anti-viral, and anti-inflammatory properties against COVID-19 virus, he has also included Ivermectin as part of his protocol.

Dr. Zelenko is now investigating the use of nebulized hydroxychloroquine, which could very well prove to be the final nail in the coffin for the SARS-CoV-2 pandemic. If you are interested in the inside story of how Dr. Zelenko discovered the Zelenko protocol, it is best told in his interview with Dr. Breggin [backup]. Dr. Zelenko has been banned from twitter, but you can keep up with him on Telegram.

The Eastern Virginia Medical School maintains an interesting website with current information for medical practitioners. They recommend the I-MASK+ and MATH+ treatment protocols for hospitalized patients. They are currently strongly advocating in favor of ivermectin instead of hydroxychloroquine, and they also recommend using quercetin combined with vitamin C as a zinc ionophore.

Zelenko Covid-19 Prophylaxis Protocol

Prophylaxis is an action taken to prevent or protect against a specified disease. Greek in origin, from the word "phylax", meaning "to guard" and "watching." 

Low Risk Patients

Young healthy people do not need prophylaxis against Covid 19.  In young and healthy people, this infection causes mild cold-like symptoms.  It is advantageous for these patients to be exposed to Covid-19, build up their antibodies and have their immune system clear the virus.  This will facilitate the development of herd immunity and help prevent future Covid-19 pandemics.  However, if these patients desire prophylaxis against Covid-19, then they should take the protocol noted below.

Moderate Risk Patients

Patients from this category are healthy but have high potential viral-load exposure.  This group includes medical personnel, caregivers of high-risk patients, people who use public transportation, first responders and other essential personnel who are crucial to the continued functioning of society.  These patients should be encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.

High Risk Patients

Patients are considered high risk if they are over the age of 45, or if they are younger than 45 but they have comorbidities, that is, they have other health conditions that put them at risk.  These patients have between a 5 to 10% mortality rate if they are infected with Covid-19.  These patients should be strongly encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.

Protocol for Low Risk Patients: 

Do nothing 

Completely optional

Elemental Zinc 25mg 1 time a day (PubMed(Amazon)
Vitamin D3 5000 iu 1 time a day (vdnmeta.com) (Amazon)
Vitamin C 250 - 500 mg 1 time a day (PubMed(Amazon)
Quercetin 250 mg 1 time a day until a safe and efficacious vaccine becomes available (J. Agric. Food Chem. 2014(Amazon)

If Quercetin is unavailable, then use Epigallocatechin-gallate (EGCG) 200mg 1 time a day (J. Agric. Food Chem. 2014

Protocol for Moderate / High Risk Patients:

Hydroxychloroquine (HCQ) 200mg once a day for 5 days, then HCQ 200-400mg one time a week (ScienceDirect)
Vitamin D3 5000 IU/day or 50000 IU once a week (Amazon)
Vitamin C 1000mg once a day (Amazon)
Zinc 25-50mg/day (Amazon)


Ivermectin 0.2 mg/kg — one dose on day 1 and day 3, then take one dose weekly (ivmmeta.com).
Vitamin D3 5000 IU/day or 50000 IU once a week
Vitamin C 1000mg once a day 
Quercetin 500mg/day 
Zinc 25-50mg/day

Editor's Note: If you simply cannot get hydroxychloroquine or ivermectin, quercetin is a viable stand-in. Quercetin works best when taken with vitamin C and Bromelain, as vitamin C helps activate it and bromelain helps with the absorption. 

Zelenko Protocol - Treatment Plan for Patients with Covid-19 symptoms

Fundamental Principles (Dr Zelenko Protocol When to Start)

Treat patients based on clinical suspicion as soon as possible, preferably within the first 5 days of symptoms. Perform PCR testing, but do not withhold treatment pending results.

Patient Categories

Low risk patient - Younger than 45, no co-morbidities, and clinically stable
High risk patient - Older than 45, younger than 45 with co-morbidities, or clinically unstable

Treatment Options

Low risk patients - over the counter options:

1. Elemental Zinc 50mg 1 time a day for 7 days (PubMed) (Amazon)

2.1. Quercetin 500mg 2 times a day for 7 days (PubMed) (AmazonOR

2.2. Epigallocatechin-gallate (EGCG) 400mg 1 time a day for 7 days (J. Agric. Food Chem. 2014)

3. Vitamin C 1000mg 1 time a day for 7 days (Amazon)
4. Vitamin D3 5000iu 1 time a day for 7 days (Amazon)

Moderate / High risk patients

Hydroxychloroquine (HCQ) 200mg 2 times a day for 5-7 days (ScienceDirect)


Ivermectin 0.4-0.5mg/kg/day for 5-7 days (ivmmeta.com).

Either or both HCQ and IVM can be used, and if one only, the second agent may be added after about 2 days of treatment if obvious recovery has not yet been observed etc.

If HCQ is not available, Quercetin 500mg 3 times a day for 7 days OR
EGCG 400mg 2 times a day for 7 days

In combination with the above (AND):

1. Elemental Zinc 50 - 100 mg 1 time a day for 7 days (Amazon)

2. Hydroxychloroquine (HCQ) 200mg 2 times a day for 7 days  

3. Azithromycin 500mg 1 time a day for 5 days or 

Doxycycline 100mg 2 times a day for 7 days

4. Vitamin C 1000 mg 1 time a day for 7 days (Amazon)

5. Vitamin D3 10,000 IU 1 time a day for 7 days (Amazon)

Both protocols can be viewed and downloaded from his website.

Note on Zinc supplements: How much zinc you should take per day depends on the type and forms of zinc, as each supplement contains a different amount of 'elemental zinc'. The percentage of elemental zinc varies by form. 

For example, approximately 23% of zinc sulfate consists of elemental zinc; thus, 220 mg of zinc sulfate contains 50 mg of elemental zinc (Ref). Zinc picolinate (20% of elemental zinc), zinc ascorbate (15%), zinc chloride (48%), zinc carbonate (52%), zinc citrate (31%), zinc bisglycinate (25%) (Ref) and zinc gluconate (14%) and zinc oxide (80%) (Ref).

About Dr Vladimir Zelenko

He graduated with a B.A. degree with high honors in Chemistry from Hofstra University. After receiving an academic scholarship to attend S.U.N.Y. at Buffalo School of Medicine, he earned his M.D. degree in May 2000. Dr. Zelenko completed his family medicine residency at South Nassau Communities Hospital in Oceanside, N.Y. in May 2004. Since then, Dr. Zelenko has practiced family medicine in New York’s Hudson Valley. He has been described by his patients as like a family member to thousands of families, and is a medical adviser to the volunteer ambulance corps in Kiryas Joel, New York.

When asked about studies that seemed to discredit the efficacy of HCQ in treating the Chinese coronavirus, Zelenko explained “You don’t fire a gun without a bullet in it and then say the gun doesn’t work when you don’t kill the target. The studies that were done on HCQ did not include the use of Zinc.  HCQ is what opens the cell and enables Zinc to attack the virus. One is not effective without the other, or without a suitable substitute for HCQ. The studies were designed to fail.”

Dr. Zelenko says that both prophylaxis measures and actual case treatments need to be customized to the individual. As a general rule, he says, those people who are in the higher risk groups, both by age and by other pre-existing conditions, require more aggressive actions on both the preventative and diagnostic side.

“This virus remains relatively stable inside the host for about the first five days,” Zelenko says. “After that it starts to multiply rapidly. It also starts to migrate from sinus to lungs and cardio areas where involvement becomes more severe and treatment becomes more difficult. The key is early intervention.” Zelenko again mentioned his 84% success rate in high-risk patients.

Scientific Papers from Dr. Zelenko and his collaborators

Documents from Dr. Zelenko

Video updates from Dr. Vladimir Zelenko

Dr. Zelenko provides video updates on the Rabbi Aryeh Katzin youtube channel. As a precaution against social media censorship, the video updates have been backed up on bitchute, an alternate video platform that supports freedom of speech. Videos labeled (censored by YouTube) were deleted/censored by YouTube. Videos labeled (censored) were set to private mode by Rabbi Katzin, as a result of the chilling effect of social media censorship, to prevent deletion of his youtube channel.

04/19/2020: Dr. Zelenko on the latest statistical clinical outcomes of his treatment.
[youtube link] (censored) ||[bitchute]
04/30/2020: Dr. Zelenko responds to the VA study and his plans to publish his data in observational peer-reviewed research papers.
[youtube link] (censored) ||[bitchute]
05/03/2020: Updates on the adoption of Dr. Zelenko's treatment protocol by Honduras, Brazil, Ukraine, Israel, Italy, Turkey, Iran, as well as ongoing current research efforts. He also.explains the mechanism of action underlying his treatment regimen.
[youtube link]||[bitchute]
05/12/2020: Update focuses on policy recommendations for dealing with a likely second wave of the SARS-CoV-2 virus.
[youtube link] (censored) ||[bitchute]
05/17/2020: Update on the efficacy of adding zinc to the hydroxychloroquine treatment. Dr. Zelenko explains his prophylactic protocol using hydroxychloroquine and zinc at a reduced dosage. Also some autobiographical notes about the importance of thinking outside the box when facing an unusual challenge.
[youtube link -- part 1] (censored) || [youtube link -- part 2] ||[bitchute -- part 1]||[bitchute -- part 2]
05/24/2020: Latest updates on collaboration with Brazil, comments on Lancet study, crowdprotocol.com, opening the economy safely, availability of medications, quercetin, dosage of elemental zinc, and the clinical trial at St. Francis hospital.
[youtube link] (censored) ||[bitchute]
05/28/2020: Latest updates on research publication, the politics of censorship, and the meaning of life.
[youtube link] (censored) ||[bitchute]
06/09/2020: Dr. Zelenko on the Lancet, NEJM Retracted Studies on the hydroxychloroquine treatment protocol. Also other updates and commentary.
[youtube link] (censored) ||[bitchute]
06/21/2020: Dr. Zelenko comments on the revocation of the Emergency Use Authorization of hydroxychloroquine by the FDA. Announces that his research paper has been submitted for publication and a preprint will be published soon. Also some very interesting comments on the spititual basis of what motivates him.
[youtube link] (censored) ||[bitchute]
07/03/2020: Dr. Zelenko shares the good news that his first paper is now publicly available in preptint form.
[youtube link] (censored) || [bitchute]
07/10/2020: Dr. Zelenko communicates some optimism amongst all the fearmongering. World leaders are aware of his research paper. Dr. Zelenko announces his website thezelenkoprotocol.com and encourages that we reach out to our political leaders.
[youtube link] (censored) || [bitchute]
07/10/2020: This video has no new medical information but is still very interesting. Defeating this pandemic now comes down to making moral choices: service to self vs service to others.
[youtube link] || [bitchute]
07/21/2020: Dr. Zelenko speaks about the purpose of life while in anticipation of open heart surgery. This is a very heartfelt and deep video about both the current pandemic, and more broadly about living on a razor's edge between chaos and order.
[youtube link] || [bitchute]
08/06/2020: Dr. Zelenko gives his latest update about the FDA rules on EUA, research studies on HCQ, and social media censorship.
[youtube link] (censored) || [bitchute]
08/09/2020: Dr. Zelenko updates us on his White House petition, gives the dosage recommendation for prophylactic and treatment quercetin protocols, and suggests possible RCT studies to determine whether his HCQ protocol can be used against the influenza virus.
[youtube link] (censored) || [bitchute]
08/10/2020: Dr. Zelenko updates us about several topics, including the current political situation with HCQ, the quercetin protocol, his use of ivermectin and anti-coagulants as adds-on to the Zelenko protocol, the socond SARS-CoV-2 wave, vaccine safety and effectiveness, and the telemed program by Dr. Jerome Corsi.
[youtube link] (censored by YouTube) || [bitchute]
08/12/2020: Dr. Zelenko comments on the FDA decision to deny the Henry Ford Health System request to use hydroxychloroquine
[youtube link] || [bitchute]
08/16/2020: Dr. Zelenko presents his updated treatment protocol, incorporating the quercetin protocol for low-risk patients, and additional medications to the baseline Zelenko protocol for select patients.
[youtube link] (censored) || [bitchute]
08/19/2020: Dr. Zelenko updates us on a possible EUA process violation by the FDA and on his updated treatment protocol
[youtube link] || [bitchute]
08/19/2020: Dr. Zelenko shares his thoughts about death and the meaning of life.
[youtube link] || [bitchute]
08/26/2020: Dr. Zelenko comments on the new Italian study that reported 30% reduction of mortality. Also makes some political comments on the suppression of the Zelenko protocol that seem to have prompted YouTube to censor the video.
[youtube link] (censored by YouTube) || [bitchute]
08/26/2020: Dr. Zelenko: Communism vs Capitalism. What is definition of success?
[youtube link] || [bitchute]
09/03/2020: Latest updates on how to respond to the second wave, the importance of beginning treatment immediately, reinfections, youtube censorship, freedom vs tyranny, the safety profile of remdesivir and hydroxychloroquine.
09/03/2020: Dr. Zelenko makes interesting comments on the Rosh Hashanah and spirituality. Not medically related, but very interesting nonetheless.
09/11/2020: Dr. Zelenko comments on prophylaxis against SARS-CoV-2 and facemasks. He notes that mortality rates have decreased not necessarily because the virus has weakened, but because people seek early treatment and because some doctors prescribe the appropriate therapeutics. Also mentions receiving an email from a village in Pakistan where the Zelenko protocol is being used. Finally comments on the anniversary of the September 11 terrorist attack, and the underlying philosophical conflicting worldviews.
[youtube link] || [bitchute]
09/29/2020: Dr. Vladimir Zelenko Shared His Concerns About People Still Getting COVID-19 Symptoms
[youtube link] || [bitchute]
10/06/2020: Discussion of censorship of both Rabbi Katzin's YouTube channel and Dr. Zelenko's twitter account and how it should be addressed. Comments on the treatment protocol used by POTUS. Also discussion of how to protect yourself from the virus (considerations include prophylaxis, immunity, facemask, vaccine safety and efficacy, standard of care).
[youtube link] || [bitchute]
10/16/2020: Dr. Zelenko updates us about his upcoming invited oped to the Jerusalem Post. Also comments on the latest study concerning remdesivir. Finally comments on the Zelenko protocol, the art of medicine, and how to custom-tailor treatment for each patient.
[youtube link] || [bitchute]
10/30/2020: Dr. Zelenko's research paper published on 26 October 2020 in the The International Journal of Antimicrobial Agents. Fight the second wave of SARS-CoV-2 by being prepared.
[youtube link] || [bitchute]
10/30/2020: Faith or Knowledge? Finding strength in the midst of adversity.
[youtube link] || [bitchute]
11/15/2020: Dr. Zelenko provides an update on the current political situation and also on an upcoming Senate hearing by Senator Ron Johnson on early treatment. Also comments on the necessary general public health policy, mask mandates, antibofy and t-cell immunity testing, quarantine policies, the importance of adapting treatment protocols to individual patients, and the vaccine. This is a must-watch interview.
[youtube link] || [bitchute]
12/30/2020: Dr. Zelenko announces his new website, in response to censorship by twitter. Also comments on the vaccine, reinfections, and the new mutation of the SARS-CoV-2 virus, and t-cell immunity. Note that the youtube version is abbreviated, to avoid censorship.
[youtube link] || [facebook] || [bitchute]
01/24/2021: Say No to Covid-19 Anxiety.
[youtube link] || [bitchute]
02/01/2021: Dr. Zelenko's brief statement on the covid vaccines
[youtube link] || [bitchute]
02/01/2021: Dr. Zelenko's statement on the Israeli vaccine policy
[facebook] || [bitchute]

Other video updates from Dr. Zelenko are listed below:

03/28/2020: Dr. Zelenko's first bombshell interview with Rudy Giuliani.
[youtube link] || [bitchute]
07/01/2020: Dr. Zelenko's second interview with Rudy Giuliani.
[youtube link]
08/04/2020: Dr. Zelenko interviewed by Debbie Aldrich on the war against hydroxychloroquine.
[youtube link] || [bitchute]
09/03/2020: Dr. Zelenko Discusses COVID-19 Outpatient Management with Dr. Been
[youtube link] || [bitchute]
09/30/2020: Dr. Zelenko interview by Simone Smith of the Toronto Carribean News.
[brighteon] || [bitchute] || Brighteon is blocked by social media. Share this article to bypass censorship
10/11/2020: Barry Shaw of "The View from Israel" interviews Professor Harvey Risch and Dr. Vladimir Zelenko who challenge the assumptions of health officials with science, facts, and evidence of fraud.
[youtube link] || [bitchute]
11/03/2020: Dr. Vladimir Zelenko talks with John Mappin about his success with Hydroxychloroquine
[youtube link] || [bitchute]
11/17/2020: The Zelenko Early Treatment Study, the Role of Zinc, the Therapeutic Approach to COVID-19 in Germany
[covexit] || [youtube link] || [bitchute]
12/09/2020: Dr. Zelenko curing Covid19 patients without fanfare! (interview by Dr. Carole Lieberman)
12/14/2020: Dr. Zelenko interview by Patriot Transition
[youtube link] || [bitchute]
12/16/2020: Dr. Zelenko interview by Patriots in Tune
[youtube] (censored) || [bitchute]
12/16/2020: Dr. Zelenko interview by Del Bigtree
12/16/2020: Dr. Zelenko interview by John Mappin
[youtube] || [bitchute]
12/23/2020: Red Dawn News interview w/ Dr. Zelenko Pt 1 of 2
[youtube link] || [rumble] || [bitchute]
12/25/2020: Talkline With Zev Brenner Interviews Dr. Zev Zelenko
[youtube link]
12/26/2020: Dr. Zev Zelenko on Covid-19 Vaccination Tyranny and Dangers
12/27/2020: Red Dawn News interview w/ Dr. Zelenko Pt 2 of 2
[youtube link] || [bitchute]
01/08/2021: Dr. Zelenko: Steps can be taken to reduce deadliness of COVID-19
01/08/2021: Dr. Zelenko 2nd interview with the TCN TV Network
01/28/2021: Dr. Zelenko: Interview with Dr. Peter Breggin. This is a very profound interview and should be watched more than once.
[youtube link] || [bitchute] || [newtube]
02/06/2021: Dr. Zelenko's interview with Laura Eisenhower
02/26/2021: ASIA PACIFIC TODAY. Early treatment of Covid-19 saves lives with Dr Vladimir Zelenko.
03/04/2021: Dr. Zelenko with Dr. Peter Breggin: Physical and Spiritual Survival During COVID-19
[youtube] || [bitchute]

Other interviews:

04/25/2020: Dr. Dave Janda speaks with Michigan Rep. Karen Whitsett about her recent experiences with surviving the SARS-CoV-2 virus.
[youtube link] || [bitchute]
08/18/2020: Covid. "Better illegally alive than legally dead!" Barry Shaw (IISS) speaks to a doctor and a patient who tell of their harrowing experiences with Covid. Also included. Mark Levin interviews Professor Harvey Risch.
[youtube link] || [bitchute]
08/23/2020: Mark Levin Interviews Dr. Harvey A. Risch about HCQ, FDA, and Dr. Fauci.
[youtube link] || [bitchute]
08/23/2020: See the Dr. Scott Atlas interview censored by youtube.
(censored by YouTube) || [banned.video] || [bitchute]
09/15/2020: COVID-19 Management With Dr. Paul Marik - Author Of MATH+ Protocol
[youtube link] || [bitchute]
09/15/2020: Dr. Stella Immanuel interview by Simone Smith of the Toronto Carribean News.
[brighteon] || Brighteon is blocked by social media. Share this article to bypass censorship
08/17/2020: SARS-CoV2 and the Rise of Medical Technocracy. Lee Merritt, M.D.
[youtube link]
10/11/2020: 20min presentation: Ambulatory Treatment of COVID-19. Peter McCullough, MD
[youtube link] || [bitchute] || [rumble]
10/14/2020: Interview with Dr George Fareed, MD Part I
[youtube link] || [link] || [minds] || [bitchute]
10/16/2020: Interview with Dr George Fareed, MD Part II
(censored on YouTube) || [link] || [minds] || [bitchute]
11/15/2020: Dr. Stella Immanuel interview by Candance Owens.
[youtube link] || [bitchute]
12/04/2020: The FLCCC Alliance press conference from Houston, Texas
[youtube link]
12/10/2020: Dr. Peter McCullough interview with Dr. Peter Breggin: Peter A. McCullough, MD, MPH--Save Yourself, Your Family, the World From COVID-19
[youtube link] || [bitchute]
12/22/2020: Dr. Peter McCullough interview with Dr. Peter Breggin
[youtube link] || [bitchute]
01/16/2021: Bioweapons expert Dr. Lee Merrit Interview on SARS-CoV-2
[youtube link] || [bitchute]
02/03/2021: Panel of medical doctors and researchers discuss Covid-19 protection, treatments, cures, and the vaccines.
[rumble] || [bitchute]
02/11/2021: Dr. Simone Gold interview on experimental mRNA vaccines and their safety
02/13/2021: ASIA PACIFIC TODAY. Early treatment for Covid-19 reduces deaths with Dr Peter Mccullough
02/25/2021: An amazing interview with Leah Wilson by Dr. Peter Breggin: Finding the Courage to be True to Yourself and America
[youtube] || [bitchute]


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Supplements you can purchase from Amazon for COVID-19 prevention. Inspired by the FLCCC prevention protocol >



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