Z-Stack (Zelenko) Supplement Vitamins Review 2021
Z-Stack Vitamin cocktail provides key ingredients needed in order to help your body fight off this deadly invader.
The Science behind Zinc, Quercetin, Vitamin D and C to Optimize the Immune System to Fight COVID-19Recent data, from peer reviewed studies, scientific data and clinical trials show that synergistic supplement combinations involving zinc and the zinc ionophore quercetin may be effective antiviral prevention and therapeutic agents against COVID-19. An ionophore transports molecules inside cell membranes. COVID-19 viral entry and replication in cells is inhibited by zinc - significantly reducing COVID-19 infection and mortality (Source). Generally, the more zinc that can be brought into respiratory cells, the better off a COVID-19 patient will be.
Quercetin has been shown to inhibit proinflammatory cytokine production as well as inflammation due to its antioxidant properties, amongst others. By inhibiting destructive inflammation and potentially the entire cascade, quercetin may prevent severe damage to the respiratory system amongst other organs (source).
Zinc is a well known supplement that is generally contained in standard multivitamins. It provides immune support amongst other functions. Zinc inhibits coronavirus replication and is a general stimulant of antiviral immunity (source). Higher levels of intracellular zinc showed to increase intracellular pH; which affect on RNA-dependent RNA polymerase and decreases the replication mechanism of RNA viruses (e.g. COVID-19). Therefore, zinc ionophores (e.g. Quercetin) can likely be used with zinc supplement to act as antiviral against many RNA viruses including influenza and COVID-19. Suggested benefits of zinc supplementation along with zinc ionophores to prevent and treat COVID-19 and other respiratory tract infections are supported by countless studies (source). In most cases, prophylactic and early use of zinc supplementation was more effective than late therapeutic proceedings. Up to 30% of the everyday respiratory infections, briefly named “common cold,” are due to infections with coronaviruses. Studies showed reduced symptom severity, reduced frequency, and duration of the common cold after zinc administration depending on dosage, zinc compound and the start time after initial symptoms (source).
In short, a balanced zinc homeostasis is essential. Zinc supplementation improves the mucociliary clearance, strengthens the integrity of the epithelium, decreases viral replication, preserves antiviral immunity, attenuates the risk of hyper-inflammation, supports anti-oxidative effects and thus reduces lung damage and minimizes secondary infections. Especially older subjects, patients with chronic diseases and most of the remaining COVID-19 risk groups would most likely benefit.
The link between vitamin D and viral infections arose from the observation of the seasonality of vitamin D with lower levels in the winter and concomitant increases in influenza. Conversely, in summer, serum levels of Vitamin D increase and influenza virtually disappears, except during pandemics. Even in pandemics, most deaths occur during cold months.
Zelenko Covid-19 Prophylaxis Protocol
Low Risk Patients
Young healthy people do not need prophylaxis against Covid 19. In young and healthy people, this infection causes mild cold-like symptoms. It is advantageous for these patients to be exposed to Covid-19, build up their antibodies and have their immune system clear the virus. This will facilitate the development of herd immunity and help prevent future Covid-19 pandemics. However, if these patients desire prophylaxis against Covid-19, then they should take the protocol noted below.
Moderate Risk Patients
Patients from this category are healthy but have high potential viral-load exposure. This group includes medical personnel, caregivers of high-risk patients, people who use public transportation, first responders and other essential personnel who are crucial to the continued functioning of society. These patients should be encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.
High Risk Patients
Patients are considered high risk if they are over the age of 45, or if they are younger than 45 but they have comorbidities, that is, they have other health conditions that put them at risk. These patients have between a 5 to 10% mortality rate if they are infected with Covid-19. These patients should be strongly encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.
Elemental Zinc 25mg 1 time a day (PubMed) (Amazon)
Vitamin D3 5000 iu 1 time a day (vdnmeta.com) (Amazon)
Vitamin C 250 - 500 mg 1 time a day (PubMed) (Amazon)
Quercetin 250 mg 1 time a day until a safe and efficacious vaccine becomes available (J. Agric. Food Chem. 2014) (Amazon)
If Quercetin is unavailable, then use Epigallocatechin-gallate (EGCG) 200mg 1 time a day (J. Agric. Food Chem. 2014)
Hydroxychloroquine (HCQ) 200mg once a day for 5 days, then HCQ 200-400mg one time a week (ScienceDirect) (Find a Doctor)
Vitamin C 1000mg once a day (Amazon)
Zinc 25-50mg/day (Amazon)
Ivermectin 0.2 mg/kg — one dose on day 1 and day 3, then take one dose weekly (ivmmeta.com) (Find a Doctor).
Vitamin D3 5000 IU/day or 50000 IU once a week
Vitamin C 1000mg once a day
Zelenko Protocol - Treatment Plan for Patients with Covid-19 symptoms
Fundamental Principles (Dr Zelenko Protocol When to Start)
Patient CategoriesLow risk patient - Younger than 45, no co-morbidities, and clinically stable
High risk patient - Older than 45, younger than 45 with co-morbidities, or clinically unstable
Low risk patients - over the counter options:
2.2. Epigallocatechin-gallate (EGCG) 400mg 1 time a day for 7 days (J. Agric. Food Chem. 2014)
Ivermectin 0.4-0.5mg/kg/day for 5-7 days (ivmmeta.com) (Find a Doctor)
Either or both HCQ and IVM can be used, and if one only, the second agent may be added after about 2 days of treatment if obvious recovery has not yet been observed etc.
If HCQ is not available, Quercetin 500mg 3 times a day for 7 days OR EGCG 400mg 2 times a day for 7 days.
1. Elemental Zinc 50 - 100 mg 1 time a day for 7 days (Amazon)
2. Hydroxychloroquine (HCQ) 200mg 2 times a day for 7 days (Find a Doctor)
3. Azithromycin 500mg 1 time a day for 5 days OR Doxycycline 100mg 2 times a day for 7 days
4. Vitamin C 1000 mg 1 time a day for 7 days (Amazon)
5. Vitamin D3 10,000 IU 1 time a day for 7 days (Amazon)
- Dexamethasone 6-12mg 1 time a day for 7 days or Prednisone 20mg twice a day for 7 days, taper as needed.
- Budesonide 1mg/2cc solution via nebulizer twice a day for 7 days.
- Blood thinners (i.e. Lovenox, Eliquis, Xarelto, Pradaxa, Aspirin).
- Colchicine 0.6mg 2-3 times a day for 5-7 days.
- Monoclonal antibodies.
- Home IV fluids and oxygen.
About Dr Vladimir ZelenkoHe graduated with a B.A. degree with high honors in Chemistry from Hofstra University. After receiving an academic scholarship to attend S.U.N.Y. at Buffalo School of Medicine, he earned his M.D. degree in May 2000. Dr. Zelenko completed his family medicine residency at South Nassau Communities Hospital in Oceanside, N.Y. in May 2004. Since then, Dr. Zelenko has practiced family medicine in New York’s Hudson Valley. He has been described by his patients as like a family member to thousands of families, and is a medical adviser to the volunteer ambulance corps in Kiryas Joel, New York.
When asked about studies that seemed to discredit the efficacy of HCQ in
treating the coronavirus, Zelenko explained “You don’t fire a gun without a bullet in it and then say the gun
doesn’t work when you don’t kill the target. The studies that were done on
HCQ did not include the use of Zinc. HCQ is what opens the cell and
enables Zinc to attack the virus. One is not effective without the other,
or without a suitable substitute for HCQ. The studies were designed to
Dr. Zelenko says that both prophylaxis measures and actual case treatments need to be customized to the individual. As a general rule, he says, those people who are in the higher risk groups, both by age and by other pre-existing conditions, require more aggressive actions on both the preventative and diagnostic side.
“This virus remains relatively stable inside the host for about the first five days,” Zelenko says. “After that it starts to multiply rapidly. It also starts to migrate from sinus to lungs and cardio areas where involvement becomes more severe and treatment becomes more difficult. The key is early intervention.” Zelenko again mentioned his 84% success rate in high-risk patients.
Disclaimer: Always see your doctor before taking these supplements. Be aware that most of the dosages are above the recommended dietary allowance (RDA) and therefore such dosages should not be maintained on a long term basis.